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Transfusion-associated circulatory overload (TACO) - a breathtaking syndrome.

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Alexander Vlaar



Transfusion-associated circulatory overload (TACO) is the leading cause of transfusion related morbidity and mortality. The underlying mechanism for onset of TACO is unknown. The current proposal aims through a translational approach to understand the mechanisms involved in the onset of TACO and establish a basis to develop preventive and therapeutic strategies for this life threatening syndrome.

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